Consequently, in response to oxidative stress, hepatocytes stimulate necrotic and apoptotic pathways, leading to impaired liver function, worsened paracrine inflammation, and fibrogenesis [36]
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Thus the best-known "function" of B 12 (that which is involved with DNA synthesis, cell division, and anemia) is a facultative function that is mediated by B 12 -conservation of an active form of folate which is needed for efficient DNA production
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